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Monitoring Body Temperature Could Provide Early Warning for Graft-Versus-Host-Disease

By continuously monitoring the body temperature of mice that had undergone bone-marrow transplants, researchers were able to detect early warning signs of graft-versus-host disease -- a dangerous, sometimes deadly response of the transplanted immune system -- in a simple, non-invasive way.

Rogel Cancer Center names new associate directors for data and population sciences

The University of Michigan Rogel Cancer has named Bhramar Mukherjee, Ph.D., associate director for quantitative data sciences, and Christopher Friese, Ph.D., R.N., associate director for cancer control and population sciences.

An innovative way of assessing clinical trial-related imaging could reduce the kinds of errors that can distort results, study finds.

Across the country, new and experimental therapies are available to patients with cancer through clinical trials. The effectiveness of a new drug or treatment approach is often evaluated based on measurements of changes seen in patients’ tumors using a variety of imaging techniques — such as MRI, CT and PET scans.

Artificial Intelligence Device May Identify Which Cancer Cells will Attack the Brain

Not all cancer cells are created equal. Only a small number of cells in a patient’s initial tumor may have the power to travel through the blood, cross the protective membrane known as the blood-brain barrier, and directly attack the brain. But which cells? What makes them special? How can we target them? Which drugs are they vulnerable to? How likely is it that a patient’s initial tumor will metastasize to the brain?

Patients want to be asked before any medical information is used for research

The majority of patients in the study thought it was important to conduct medical research using de-identified electronic health records. Support for academic medical centers or community hospitals seeking to improve quality was high, but fewer people were comfortable with insurance companies or drug companies using their data, as well as hospitals using their data for marketing purposes.

Aggressive Breast Cancer Spreads Due to Stored Energy

A U-M Rogel Cancer Center study found aggressive breast cancer cells stored high amounts of energy which enabled them to spread. This suggests a potential target in the metabolism that could slow or prevent breast cancer metastasis.

Acupressure Helps Breast Cancer Survivors with Pain, Depression, Anxiety and Sleep Problems

Breast cancer survivors reported improvements in depression, pain, anxiety and sleep after self-administered acupressure.

New Treatment Combination for Pancreatic Cancer Shows Promising Results

A clinical trial testing a new pancreatic cancer drug had promising initial results, say University of Michigan Rogel Cancer Center researchers in the Journal of Clinical Oncology. Investigators ran a phase 1 clinical trial that looked at AZD1775, an inhibitor designed to block an enzyme called Wee1, which plays a role in repairing damaged DNA. The trial builds on almost 20 years of research at U-M focused on improving the treatment of pancreatic cancer cases that are too advanced for surgery.

Prostate Cancer Mortality is Higher in Black Men

Black men are more likely to be diagnosed with prostate cancer and nearly 2.5 times more likely to die of the disease compared to non-Hispanic white men. The question is why. Are black men more likely to carry genes that drive deadlier forms of the disease? What societal disparities might be affecting outcomes?

FDA Recommendations for Breast Implants After Mastectomy

Recently, the Food and Drug Administration recommended that patients considering breast implants — whether for reconstructive surgery after a mastectomy or cosmetic surgery — receive detailed information about potential complications and rare health risks that can occur.

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