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U-M Rogel Cancer Center Urges Priority Access to the COVID-19 Vaccines for Cancer Patients and Survivors

130 organizations and cancer centers underscore the importance of prioritizing patients with active cancer and survivors of cancer for lifesaving COVID-19 vaccines.

4 Rogel Cancer Center members named AAAS fellows

Four Rogel Cancer Center members earned election to the American Association for the Advancement of Science in 2024. The AAAS is the world’s largest general scientific society. Fellows are elected for their “efforts on behalf of the advancement of science, or its applications, are scientifically or socially distinguished.”

Lighting up cancer cells with biolasers

Researchers from the University of Michigan have developed a way of detecting circulating tumor cells in the bloodstream of pancreatic cancer and lung cancer patients. As tumors develop, they shed cells into the bloodstream. Although these circulating tumor cells are vastly outnumbered by millions of other blood cells, detecting them early can potentially improve treatment outcomes.

How breast cancer cells survive in bone marrow after remission

A study from researchers at the University of Michigan and the University of California San Diego has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted therapies. The paper, “Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels,” appears in the Journal of Clinical Investigation.

Enzyme identified as new therapeutic target for “cold” tumors

Drugs that suppress UBA1 could make immune checkpoint blocking immunotherapy effective for patients with prostate cancer and other “cold” tumors

Why are more young people being diagnosed with cancer?

Researchers are investigating causes of early-onset cancer — and how to reduce your risk

Rogel Cancer Center at AACR 2025

Rogel Cancer Center and University of Michigan researchers will be represented in more than 60 presentations and poster sessions. Check the list below to support your colleagues. All times listed are Central Time.

An emerging class of RNA fighting cancer, infectious and genetic diseases

Cancer antigen-encoding RNA vaccines, or circRNA, is a targeted technology that improves existing immunotherapy and vaccine approaches

Histotripsy can help release HER2 from cancer tumor cells

A revolutionary new therapy, called histotripsy uses soundwaves to destroy liver tumors and was approved for clinical use by the FDA in 2023. A recent study in the journal Cancers demonstrates how histotripsy could stimulate the immune system to destroy a cancer through the release of tumor antigens.

Re-purposed FDA-approved drug could help treat high-grade glioma

Avapritinib, an FDA-approved drug used to treat other types of cancer, also decreases aggressive gliomas in animal models and in an initial cohort of patients with high-grade glioma

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