Proteomics Resource Facility

The mass spectrometry-based Proteomics Resource Facility (PRF) at the Department of Pathology assists researchers in designing proteomic experiment, maintain state-of-the-art instrumentation, provide technical expertise and bioinformatic support during both discovery and validation phases of proteomic experiments.

Services:

• Peptide and protein identification
• Analysis of protein-protein interactions and complexes
• Shotgun proteomic profiling
• Post-translational modifications analysis
• Protein quantification and differential expression analysis using labeling and label-free approaches
• Targeted quantification of selected peptides and proteins of interest

Major Equipment

• Orbitrap Fusion (with ETD) mass spectrometer
• Q Exactive HF mass spectrometer
• UPLCs for peptide and protein separation