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A one-two punch for brain tumors? New clinical trial opens at U-M

Gene therapy developed by Dr. Maria Castro and Dr. Pedro Lowenstein will now get the first test in human patients. The experimental approach, based on their research while at the University of Michigan, delivers two different genes directly into the brains of patients following the operation to remove the bulk of their tumors.

BMT Clinical Trials

At the University of Michigan Rogel Cancer Center, our MPN and Systemic Mastocytosis Clinic has a number of studies underway. Most are available only to our patients. We have extensive experience in selecting the right trial for each person.

Below is a list of open trials. If you see one you may be eligible for, please call 800-865-1125 (Monday-Friday, 8am-5pm EST) to learn more.

Breast cancer research at U-M benefits from multi-platform charitable shoe sale on QVC

The content on this page is out of date. To learn about fundraising events, please visit the Community Events page. To learn more about supporting the U-M Rogel Cancer Center, please visit our Make a Gift webpage.

Brain tumors fly under the body's radar like stealth jets, new U-M research suggests

Like a stealth fighter jet, the coating means the cells evade detection by the early-warning immune system that should detect and kill them. The stealth approach lets the tumors hide until it’s too late for the body to defeat them.

Gut microbiome analysis improved noninvasive colorectal cancer screening

Analysis of the gut microbiome more successfully distinguished healthy individuals from those with precancerous adenomatous polyps and those with invasive colorectal cancer compared with assessment of clinical risk factors and fecal occult blood testing, according to a new study.

Maize and Blue Go Pink at the Somerset Collection for breast cancer research

The content on this page is out of date. To learn about fundraising events, please visit the Community Events page. To learn more about supporting the U-M Rogel Cancer Center, please visit our Make a Gift webpage.

U-M researchers find protein that fuels repair of treatment-resistant cancer cells

University of Michigan researchers have found that a particular protein -- TRIP13 -- encourages those cancer cells to repair themselves. And they have identified an existing chemical that blocks this mechanism for cell repair. And they have identified an existing chemical that blocks this mechanism for cell repair. "This is a very significant advance, because identifying the function of the protein that fuels the repair of cancer cells and having an existing chemical that blocks the process, could speed the process of moving to clinical trials," said principal investigator Nisha D'Silva, U-M professor of dentistry and associate professor of pathology.

Prostate cancer in young men – more frequent and more aggressive?

The number of younger men diagnosed with prostate cancer has increased nearly 6-fold in the last 20 years, and the disease is more likely to be aggressive in these younger men, according to a new analysis.

Study sheds light on racial disparity in colon cancer

African-Americans with colon cancer are half as likely as Caucasian patients to have a type of colon cancer that is linked to better outcomes. The finding may provide insight into why African-Americans are more likely to die of colon cancer than Caucasians with the same stage of disease.

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